Project Code: 10464530
Faculty: Liggins Institute
Department: Liggins Institute
Main Supervisor: Dist Prof Jane Harding
Principal investigator: Dr Eleanor Kennedy (eken242)
Application open date: 23 Jun 2020
Application deadline: 31 Dec 2020
Enrolment information: NZ Citizens, NZ Permanent Residents, International
MRI is increasingly being used in preterm newborns to assess early brain injury and brain maturation, but its relationship to later development is unclear. We plan to determine the relationship between early MRI and later development in children who as babies took part in clinical trials of additional nutrition, or of magnesium sulphate administration to prevent cerebral palsy. If early MRI is predictive of particular problems such as cerebral palsy, it could be used in the future to identify babies at risk and allow early intervention.
We are looking for candidates with a degree in a health, psychology or education-related discipline and some experience with MRI analysis.
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We will undertake newborn MRI scanning including structural, diffusion tensor and functional imaging. Children will be assessed at two years of age for cognitive, language, motor and executive function. We will determine the relationships between early MRI findings and later developmental problems, and the effects of the trial interventions on these.
- Childhood outcomes after dextrose gel for preventing low glucose levels in babies
- Childhood outcomes after a trial of extra protein for babies born very preterm
- Do lower thresholds for diagnosis of gestational diabetes have later benefits for mothers and babies?
- Adult outcomes after repeat doses of antenatal steroids from nationally collected data
- Mid-childhood outcomes after medical interventions (i.e., dextrose gel for preventing low glucose levels or extra protein for babies born very preterm)